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Superposition of the third trajectory middle stage with the previous active GLP-1R structure (PDB: 5VAI) revealed the apo-state GLP-1R may adopt a similar extended ECD conformation as in the GLP-1-bound structure (Supplementary Fig

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Martin Lange, Executive Vice President for Development at Novo Nordisk, stated, We remain committed to the potential of once-weekly basal insulin icodec for individuals managing diabetes who require basal insulin therapy

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