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The bivariate distribution of amyloid- and tau: relationship with established neurocognitive clinical syndromes

3 Overview of NLRP3 inflammasome Innate immunity serves as the hosts primary defense barrier, wherein pattern recognition receptors (PRRs) on immune cells detect pathogen-associated molecular patterns (PAMPs), such as viral nucleic acids, bacterial lipopolysaccharides, and flagellin, or endogenous DAMPs released from damaged or dying cells

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