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Mechanisms underlying these observations have been investigated

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Why other agents often fall short for true normalization SGLT2 inhibitors / DPP-4 inhibitors: excellent value, but generally modest HbA1c lowering (often not enough to move many from clearly diabetic into normal ranges)

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2.3 Intersection gene screening and functional enrichment analysis To explore potential associations among gut microbiota, ferroptosis, and RA, Venn diagram analysis was performed on gut microbiota-related genes, ferroptosis-related genes, and RA-related genes to identify intersection genes