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There was dose-related weight loss among the retatrutide groups at 36 weeks that ranged from 3.2-16.9% compared with weight loss of 3.0% in the placebo group, and 2.0% in the dulaglutide group [4]

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A landmark analysis in The New England Journal of Medicine (STEP 1 trial, 2021) showed that participants on semaglutide lost an average of 14.9% of their body weight over 68 weeks

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