It has been suggested that keratinocytes, through the release of biological mediators, proopiomelanocortin (POMC)-derived peptides, basic fibroblast growth factor, and endothelins, regulate proliferation and differentiation of melanocytes and stimulate melanogenesis through receptor-mediated signalling pathways [20]
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Cell Mol Life Sci 82:147
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Pickart L, Vasquez-Soltero JM, Margolina A (2015) GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration
