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The Latest Recommendation According to EASO, Semaglutide and Tirzepatide should now be considered first-line drug treatments for obesity and many related conditions: Type 2 diabetes & prediabetes Cardiovascular disease Obstructive sleep apnea Knee osteoarthritis MASH (metabolic-associated steatohepatitis) Heart failure (pending more data) These medications not only support significant weight lossthey may also reduce the incidence and severity of major chronic conditions, often outperforming older therapies

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By acting on both GLP-1 and GIP receptors, Mounjaro works on multiple levels, making it a powerful tool for both diabetes and weight management

Kidney Int (2014) 85(5):106877

Increased risk of death and de novo chronic kidney disease following reversible acute kidney injury

This leads to persistent vomiting, severe pain, and an inability to keep fluids down