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Avoid caffeine, dairy, and high-fat or spicy foods as they can trigger diarrhea

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However, if you are high risk for heart disease, have had a heart event or the equivalent (stroke, stent), or do not require 15-20% weight loss, semaglutide / Wegovy may be a better choice

"For retatrutide, the findings from TRIUMPH-4 are encouraging, and with seven additional phase 3 readouts expected in 2026, we believe retatrutide could become an important option for patients with significant weight loss needs and certain complications, including knee osteoarthritis," a Lilly spokesperson said in a statement to Fox News Digital

If you need budget-friendly compounding options, see our review of the most affordable semaglutide providers

What Should I Eat Before and After Workouts on a GLP-1 to Support Muscle Recovery