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Agency feedback can mean more data collection or further analysis, which can shift this timeline

Tirzepatide, in particular, has shown dramatic reductions in hepatic fat fraction in clinical trials

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Study E: TRESIBA U-200 Administered at the Same Time Each Day as an Add-on to Metformin with or without a DPP-4 Inhibitor in Insulin Nave Adult Patients The efficacy of TRESIBA U-200 was evaluated in a 26-week randomized, open-label, multicenter trial in 457 insulin nave patients with type 2 diabetes mellitus inadequately controlled on one or more oral antidiabetic agents (OADs) at baseline