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Indications include: Medically refractory disease not responding to optimized biologic therapy Bowel obstruction from fibrostenotic stricture Intra-abdominal abscess not amenable to percutaneous drainage Complex perianal fistula (seton placement, diversion) Enterocutaneous or enterovesical fistula Dysplasia or cancer in Crohns colitis Free perforation (rare) Nutritional Therapy Exclusive enteral nutrition (EEN) effective for induction in pediatric Crohns
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doi: 10.1096/fj.00-0584fje
The honest clinical framing: BPC-157 is an experimental peptide that some patients explore as an adjunct to proven therapies or when conventional treatments have failed
Vitamin B12 injections have surged in popularity due to widespread med spa marketing and wellness influencer promotion, but genuine B12 deficiency remains a real and often underdiagnosed condition particularly among older adults
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