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For example, HepG2 cells exposed to 20 mM APAP for 24 h showed only a minor (8%) reduction in GSH content, a minor increase in protein adducts, no mitochondrial dysfunction and only a 2-fold increase in lactate dehydrogenase (LDH) release [142]

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Survodutide and orforglipron represent additional emerging molecules in this space, with orforglipron being particularly notable as an oral non-peptide GLP-1 agonist

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10.1016/j.nut.2021.111525 Nutrition

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