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Saxenda is approved for: Adults Adults with obesity (BMI of 30 kg/m or greater) Adults who are overweight (BMI of 27 kg/m or greater) and have at least one weight-related health condition, such as high blood pressure, type 2 diabetes, or high cholesterol Children aged 12 and older Adolescents with obesity who weigh more than 60 kg (132 pounds) Limitations of use Saxenda should not be used together with other medicines that contain liraglutide, such as Victoza, or with any other GLP-1 receptor agonist, such as Ozempic, Wegovy, or Trulicity The safety and effectiveness of Saxenda in children aged 12 to 17 years who have type 2 diabetes have not been established
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Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis
Both Ozempic and Wegovy have experienced supply constraints, making compounded versions legally available under federal compounding regulations
SURMOUNT-1 enrolled adults with obesity or overweight with weight-related comorbidities, demonstrating that dual agonism could achieve weight loss results that approach those seen with bariatric surgery
Patients with pre-existing hypertension taking blood pressure medications may require dose reductions or medication discontinuation as tirzepatide-induced weight loss leads to improved blood pressure control
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