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They address multiple aging hallmarks simultaneously: metabolic dysfunction, chronic inflammation, cardiovascular risk, and potentially neurodegeneration

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Overexpression of GSTP1 resulted in a two-fold increase in GSH-conjugation of the QIs, attenuated QI-induced cytotoxicity especially under GSH-depletion condition, abolished QIs-induced apoptosis but did not significantly inhibit the activation of the ER stress response

9 Many of these patients are currently using or will eventually use GLP-1 RAs