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Its mechanism involves specific engagement of AMY1R and AMY3R in hindbrain and hypothalamic circuits that regulate energy homeostasis, leading to preferential fat mass reduction and altered hypothalamic gene expression profiles [2]

Variation in glucocorticoid sensitivity and the relation with obesity

If you want a plain-language rundown of symptoms and patterns, the Crohns overview is a good place to start

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10.1021/bi700840d Biochemistry 33 SchnurrK.BelknerJ.UrsiniF.ScheweT.KhnH