While analysts were hoping to see weight loss of up to 25%, the company noted that there didn't appear to be a plateau, suggesting that greater weight loss may be achieved over a longer time frame
And now theyre accumulating evidence some strong, some preliminary for benefits across cardiovascular disease, kidney disease, fatty liver (MASH), osteoarthritis, certain cancers, and even alcohol use disorder
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The low representation of tirzepatide likely reflects its recent introduction in 2023 [11], whereas the high frequency of exenatide reports can be attributed to its earlier approval in 2005 [29]
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The inability to measure insulin also meant that for a long time diabetes was seen as a uniform disease caused by a deficiency of the hormone