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Effects of GLP-1 receptor agonists on kidney and cardiovascular outcomes Badve SV et al

Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum

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In addition, these studies suggested that these peptides may modulate food intake, cardiac tone, and sleep through apparently specific receptor agonistic action

We found an indirect effect of GLP-1RAs on SA through BMI(OR 0.86 [95%CI 0.751.00], P = 4.56 10 2 ), with a mediation proportion of 20.28% (95% CI [0.3740.16%]),and through current tobacco smoking (OR 0.95 [95%CI 0.910.99], P = 2.75 10 2 ), with a mediation proportion of 6.65% (95%CI [0.74%12.57%]).The mediating effect of alcohol consumption was not observed (P = 1.29 10 1 ) (Fig