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Menopause 31(5):p 363-371, May 2024

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In addition, under hypoxic conditions, mitochondria can promote self-digestion and regulate ROS levels through physical interactions with lysosomes, a novel structural phenomenon termed megamitochondria engulfing lysosome (MMEL) [158]

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There is some evidence to suggest that rectal administration of glutathione may benefit patients with Parkinson's disease, potentially helping to manage symptoms by combating oxidative damage within neuronal cells

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As a master antioxidant, GSH directly scavenges reactive oxygen species and serves as a co-substrate for glutathione peroxidase (GPx), underpinning critical processes including detoxification, DNA synthesis, and immune regulation

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2005 Feb;288(2):R374-83

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