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The p53 protein, a key human tumor suppressor, regulates the expression of oncogenes and downstream signaling pathways, contributing to biological effects (7275): Beyond its role in cancer, p53 is highly expressed in the brain, where it influences dendritic growth, oxidative stress response, apoptosis and autophagy, making p53 dysfunction and associated pathways noteworthy in the pathogenesis of AD (7678)

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On the other hand, a damaged peroxisome contributes to oxidative stress by directly releasing H 2 O 2 (118)

The malic acid component is a key player in the Krebs cycle, which is responsible for producing ATP, the primary fuel for muscle contractions

I.CobosI.HoK.et al (2012)