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As datasets expand beyond mostly female and mostly European samples, the promise will depend on showing that these signals can guide better choices in clinics

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According to the National Institutes of Health, losing just 5-10% of body weight can significantly improve PCOS symptoms, restore ovulatory cycles in 50-80% of patients, and enhance fertility outcomes

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Additionally, Wang et al (182) used resonance Raman scattering technology and found that intraperitoneal injection of -HB improves mitochondrial function in T2DM model mice, thereby alleviating pathological phenotypes of T2DM such as elevated blood glucose, IR, systemic inflammation and multi-organ damage