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Lastly, Group members recommended stratifying the measure by factors such as care type, region, and hospital or trauma level designation

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In laboratory and pre-clinical settings, DSIP has been studied as a uniquely multifunctional endogenous regulatory neuropeptide across sleep, stress, neuroendocrine, neuroprotection, and geroprotective research applications: Sleep biology delta-wave SWS promotion, sleep homeostasis modulation, sleep efficiency and sleep latency research Sleep EEG research delta-wave induction, SWS vs REM sleep architecture, and sleep stage analysis via polysomnography Sleep neuromodulator pharmacology DSIP vs sedatives and hypnotics

These are mechanistically different agents at opposite ends of the regulatory ladder

5.0 Pharmacological properties 5.1 Mechanism of action Glutathione is an extremely important cell protectant which directly quenches reactive hydroxyl free radicals, other oxygen-centered free radicals, and radical centers on DNA and other biomolecules

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