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The abnormal activation and polarization of innate immune cells, as well as the imbalance and autoreactivity of the adaptive immune system, jointly drive the pulmonary vascular inflammatory response

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It has been reported that long-term oral carnitine treatment for 6 months in a patient with carnitine deficiency resulted in increased muscle strength, significant reduction in heart size, relief from cardiomyopathy, and partial repletion of carnitine levels in plasma and muscle with complete repletion of liver functions (71)