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Downregulated levels of miR-101 are reported in AD brain and are consistent with in vitro studies where inhibition of miR-101 increased APP levels (Siedlecki-Wullich et al., 2021)

For this indication, it is well established, with cardiovascular outcomes data to support its use

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The AIF pathway, together with increased levels of cleaved caspase 3, is recognized as the main inductor of apoptosis in the damaged brain of neonatal rodents 38 , even if their action becomes less pronounced once the brain matures 39

Some people philosophically prefer non-injectable options