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Thus, patients taking the agents associated with the greatest weight loss, tirzepatide and semaglutide, have the highest incidence of developing both hypocalcemia and hypercalcemia

While effective, the "cold chain" requirements and injection-based delivery remain significant barriers to global scale

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Nevolat Nevolat is a generic liraglutide injection, which was available under the brand name Saxenda, and can help you lose an average 8% of your starting body weight over 56 weeks at the strongest dose

One more clinical note: the trial used a gradual titration protocol specifically to manage tolerability

L.et al (2002)