The LEADER trial (cardiovascular outcomes study in type 2 diabetes) showed that liraglutide, a similar GLP-1 agonist, reduced major adverse cardiac events by 13%
One common assay format employed is to study the effects of test compound in the presence of protease inhibitors (e.g., E64d) or bafilomycin A using LC3-II as a measure of autophagy flux
Evidence for this use is still developing and should be discussed with the treating oncology team as part of the overall care plan
Why take a drug if you dont have the disease? Sarah Rahal can be reached at [email protected]
The bigger concern often comes after the excitement
Park J, Schwardt NH, Jo J-H, Zhang Z, Pillai V, Phang S et al (2022) Shifts in the skin bacterial and fungal communities of healthy children transitioning through puberty