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6 Mais certaines tudes n'ont cependant pas russi dmontrer cette augmentation

Further medicinal chemistry optimization to improve structure activity relationship and potency as well as safety and toxicity, pharmacokinetic (bioavailability, half-life and biodistribution) and rodent in vivo studies will follow to determine the compounds potential to become suitable candidates for further development

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Dose, Duration, and Individual Risk Factors in Glutathione Depletion Acetaminophen-induced glutathione depletion is dose- and duration-dependent

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