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It is a secretagogue, and is considered to be an agonist, meaning that it possesses the ability to bind certain receptors of a cell and provokes a cellular response

Cancer Res 54 : 55315534 Karnieli E, Werner H, Rauscher II FJ, Benjamin LE, LeRoith D (1996) The IGF-I receptor gene promoter is a molecular target for the Ewing's sarcoma-Wilms' tumor 1 fusion protein

After centrifugation, methanol-containing proteins were precipitated with cold trichloroacetic acid (TCA) and reduced with 500 mM sodium borohydride in 0.2 M borate buffer (pH 9.2) after overnight incubation at room temperature