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(In other words, forgive me if I didnt define something in a way more familiar to you.) Below is a brief overview of research on mast cell activation disorders, which is an umbrella term covering several distinct diseases, including: Lets go into the first two in a little more detail, and then focus on MCAS

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Hexokinase 2 promotes tumor growth and metastasis by regulating lactate production in pancreatic cancer

Another study indicates that inhibition of MCT3 impairs the transport of lactate out of skeletal muscle, potentially promoting SMCs proliferation and facilitating the development of atherosclerosis

It plays a critical role in tissue remodeling, wound healing, collagen production, and anti-aging processes

G Mingrone reports grants and personal fees from Novo Nordisk, personal fees from Johnson & Johnson, personal fees from Fractyl Inc., during the conduct of the study