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In the Phase 2 trial, the cohorts that escalated to higher maintenance doses began at 2mg weekly and increased by 2mg every 4 weeks

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[] In experiments conducted on mouse subjects, the natural substances luteolin, ellagic acid, and punicic acid were able to limit the growth of PCa cells, which resulted in a decrease in both metastasis and angiogenesis

During IRI, the damaged tissues produce excessive amounts of ROS, causing the release of proinflammatory cytokines and apoptosis (6466)

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