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For a deeper explanation of the mechanism, our guide to whether GLP-1 can give you heartburn walks through why reflux can show up during treatment

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doi: 10.3389/fphar.2026.1740609 Received 06 November 2025 Revised 03 February 2026 Accepted 11 February 2026 Published 24 February 2026 Volume 17 - 2026 Edited by Ziyi Wang, Johns Hopkins University, United States Reviewed by Xue Xiaoyong, Beijing University of Chinese Medicine, China Yatan Li, Xinjiang Medical University, China Updates Copyright 2026 Pang, Jiang, Ge, Huang, Rao, Wang, Zhou, Lyu, Wang and Tan

For sure, standard redox potentials, with appropriate consideration of pH, temperature, and concentration effects, can tell us in which direction a reaction between different redox couples might go

2008;135(1):194-204.e3