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Acute inflammation is essential for initiating the healing process, clearing damaged tissue, and recruiting repair cells to injury sites

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Methods Computational Methods The package Schrdinger Suite 2022-4 69 , through its graphical interface Maestro 70 , was used to perform most modeling and visualization tasks

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As introduced previously, several retrospective clinical studies show that metformin treatment in diabetic patients or amnestic mild cognitive impairment patients without diabetes have slower cognitive decline and lower dementia risk (Bohlken et al., 2018