Kadowaki, "Effects of lactulose on renal function and gut microbiota in adenine-induced chronic kidney disease rats", Clinical and Experimental Nephrology
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This interaction blocks Keap1s ubiquitin-dependent degradation of NRF2, stabilizing the protein and promoting its nuclear translocation and transcription of target genes, thereby forming a p62-Keap1-NRF2 positive feedback loop
Your gut bacteria literally affect your mood On gluten: celiac is real but rare
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