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Reduced release and binding of perforin at the immunological synapse underlies the age-related decline in natural killer cell cytotoxicity
By comparing metabolite concentrations between different sample types, succinic acid and citric acid were among the highest concentration metabolites in urine compared to other samples in ovarian cancer patients ( Figure 3 )
In this reaction, CTP (cytidine triphosphate) donates a phosphate group, forming CDP-choline, an intermediate compound crucial for the final step of phosphatidylcholine synthesis
Naming the blood glucose-lowering substance 'pancreine'
This work was supported by the grants from Jiangsu Provincial Research Hospital (YJXYY202204-YSB38 and YJXYY202204-2-YSC12), and the Project of Jiangsu Degree and Graduated Students Education Association (JSYXHXM2023-ZYB19)
Ferrostatin-1 (Fer-1), deferoxamine mesylate (DFO), liproxstatin-1 (Lip-1), RSL3, Z-VAD-FMK and mitoTEMPO (MT) were purchased from Selleck (Selleck, China)
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