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Additionally, 59.1%, 53.3% and 54.2% of patients taking 5 mg, 10 mg, or 15 mg tirzepatide respectively achieved a 1-stage or greater fibrosis improvement without worsening of MASH versus 32.8% of patients on placebo

IUPHAR review Glucagon-like peptide-1 (GLP-1) and substance use disorders: An emerging pharmacotherapeutic target

Thus, the findings must be replicated in a properly designed placebo controlled clinical trials

Patel KP, Zhang PL, Krukoff TL

& Zietse, R

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