Some of these supplements may exert more of an effect than others, but we need more research to say for sure
These are valid and understandable concerns, Ryan explains
A JAMA Network Open retrospective cohort study of 125,474 adults with overweight or obesity: Patients with T2DM: 46.5% discontinued by year one 64.1% discontinued by year two Patients without T2DM: 64.8% discontinued by year one 84.4% discontinued by year two Nearly 85% of patients without diabetes stopped taking GLP-1s within two years
Struggling to Lose Weight on Obesity Drugs
She emphasizes listening to the patient, treating systemic contributors, and combining targeted tools with foundational lifestyle work
The potential protective effects of semaglutide on mental health could be due to weight loss, a decrease in food noise, some combination of the two, or an entirely different mechanism, perhaps related to GLP-1's direct effects on the brain, says Anna Lembke, MD, a psychiatry professor at Stanford Medicine in California