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The molecule isnt known to produce tolerance or downregulation that would require breaks

R&D Systems, Minneapolis, MN, USA) and treated by SP (2.5 10 6 cells/mL) or MTX (4 M) for 0, 1, 3, and 5 days

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Front Neurosci 12:214 Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E, Basavarajappa D, Radmark O, Kobayashi S, Seibt T, Beck H, Neff F, Esposito I, Wanke R, Forster H, Yefremova O, Heinrichmeyer M, Bornkamm GW, Geissler EK, Thomas SB, Stockwell BR, O'Donnell VB, Kagan VE, Schick JA, Conrad M (2014) Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

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It is made up of three amino acids : glutamine glycine cysteine What are its main functions