Most practitioners recommend 90180 days before assessing efficacy, with optional 30-day breaks between extended cycles to prevent receptor downregulation
Growth Hormone Sensitization: Increases GH receptor expression and enhances JAK2/STAT signaling (PMC6271067)
Compare this to the substances on a standard drug panel, most of which are small organic molecules with molecular weights in the range of 200 to 400 daltons, and you begin to see why immunoassay cross-reactivity is essentially impossible under normal conditions
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For example, UA-induced cytokine expression is NF- B-mediated
Both methods are generally safe when used appropriately, but they differ in nature