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Clinically, IGF-1 is used to treat patients who suffer from muscle wasting due to conditions like HIV, or patients with hormonal deficiency [1]

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For example, individuals in the cohorts were older and mostly white men, thus hurting the results generalizability to the general population, while the researchers could not rule out residual confounding

52,53,54 In contrast, in conditions such as chronic obstructive pulmonary disease, 55 idiopathic pulmonary fibrosis, 56 hypertension, 57 type II diabetes, 58 neurodegenerative diseases, 59 cancer, 13 and systemic inflammatory response syndrome, 60 redox regulation indirectly influences disease progression through signal transduction pathways

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Sleep problems : Non-restorative sleep, frequent waking, or conditions like restless legs syndrome