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Neuropharmacology (2020) 162:107813

Hypoxic conditions elevated the inflammation in steatotic hepatocytes and increased the release of EVs derived from fat-laden hepatocytes, which stimulate the activation of hepatic stellate cells and the inflammatory phenotype in Kupffer cells [111, 112]

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doi: 10.1016/j.stem.2022.11.010 141 HickmanS

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