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Inflamm-aging of hematopoiesis, hematopoietic stem cells, and the bone marrow microenvironment

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Examples of monoclonal antibodies include trastuzumab (Herceptin), dupilumab (Dupixent), pembrolizumab (Keytruda), and ocrelizumab (Ocrevus)

Hyperpolarization resulting from this mechanism will result in deactivation of voltage-dependent Ca channels, resulting in decreased Ca influx, which will favor smooth muscle relaxation

Risks: Allergic reactions, infections, or blocked blood vessels which can cause blindness or stroke

Consequently, its overall effectiveness as an injectable aesthetic treatment remains clinically unproven