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One-carbon metabolism is essential for DNA methylation and synthesis, with methionine serving as the main methyl group donor

Causes of vision loss worldwide, 1990-2010: a systematic analysis

Plasma half-life estimates range from 30-60 minutes based on limited animal and human studies, though systematic pharmacokinetic characterization in humans has not been published

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However, whether the GPX4PRDX6 interaction represents a broadly conserved ferroptosis defense mechanism or is restricted to specific cellular contexts remains to be established