Human An earlier review on pharmacotherapy for gestational diabetes reported no human data on the safety of GLP-1 agonists during pregnancy and concluded that these drugs cannot be recommended in pregnancy (30)
[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Caruso I, Di Gioia L, Di Molfetta S, et al
People with cancer (active or suspected): As mentioned previously, TB4 and TB-500 can promote the growth of new blood vessels, which could support the growth or spread of cancer.36 Professional athletes: TB4 and TB-500 are banned by the World Anti-Doping Agency (WADA)
Mental health improvements often appear now, linked to both weight loss and semaglutide's direct effects on mood-related brain regions
However, it's theoretically possible
GLP-1 medications work by supporting appetite regulation and satiety signaling, which may help address some of the biological drivers of weight gain