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Statistical analysis We used SAS Version 9.4 TS Level 1M5 X64_10PRO platform (SAS, Cary, NC, USA) 24 to perform statistical analysis of the components of metabolic syndrome, lipid panel, hepatic panel, and adiposity, oxidative stress, and inflammation biomarkers

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However, the molecular mechanisms controlling these signaling pathways are yet to be elucidated

Oxidative stress can cause DNA damage and telomere shortening (95)

In aged human pinealocytes, Epitalon selectively safeguarded cells from degenerative changes, suggesting a tissue-specific rejuvenating effect on the very gland responsible for circadian control

The upper block showed stronger signals in COPD samples than in controls, suggesting that several nicotine-responsive genes were transcriptionally activated under the COPD condition