doi: 10.1172/JCI113450 110 NorrelundHFrystykJJorgensenJOMollerNChristiansenJSOrskovHet al
Sun Exposure India receives intense UV radiation for much of the year
My team and I asked two questions: For people already struggling with addiction, did the drugs reduce overdoses, drug-related hospitalizations and deaths
The American College of Rheumatologys 2025 annual conference (ACR Convergence 2025) added to this picture, with data suggesting that patients on GLP-1 drugs had fewer rheumatic disease flares and that those with osteoarthritis saw greater improvements in pain and function compared to those on SGLT2 inhibitors, another diabetes drug class [11]
Many side effects are most noticeable early or after dose increases and often improve over days to weeks
With this breakthrough designation and alignment with the FDA on registrational Phase 3 trial parameters, we are laser-focused on strengthening the foundation of Altimmune to advance pemvidutide through late-stage development guided by our commitment to serve patients and create value for our stakeholders." Breakthrough Therapy Designation for pemvidutide in MASH was granted based on submission of 24-week data from the IMPACT Phase 2b trial demonstrating statistically significant MASH resolution without worsening of fibrosis, along with early and substantial improvements in liver fat and non-invasive tests of fibrosis and hepatic inflammation
