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It was particularly jarring, because this drug was generally regarded as being so safe, until it wasnt
Researches carried out on this topic have pinpointed many genetic variations, including genes involved in carnitine biosynthesis and glutamatergic transmission, which may augment susceptibility to neurodevelopmental disorders like ASD
It was shown that HB acts in vitro as a neuroprotective agent against the toxicity of MPTP, which induces a defect in the mitochondrial complex I of dopaminergic neurons (157)
Consequently, a reduction of the rearing rate occurred in the high-dose group only
L-carnitine 2
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