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Huannao Yicong formula (HYF) and Jiannao Yizhi formula (JYF) reduce A42 and tau protein levels, delivering comparable benefits to standard ChEIs (Yang et al., 2019
Overall, we conclude that PC patients with low expression of VRK2 are sensitive to GSH-targeting therapy, while PC patients with high expression of VRK2 are re-sensitive to GSH-targeting therapy following VRK2 inhibition, indicating genetic aberrance of VRK2 expression stratifies the response of PC to metabolism-targeted therapies
In BV2 and N2a cells treated with amyloid (A), berberine promotes cell proliferation, inhibits the activity of caspase-3, and reduces the rate of apoptosis, in addition, berberine promotes cell viability via the microRNA (miR)-188/nitric oxide synthase 1 (NOS1) pathway (Ye et al., 2009
Macrophage-derived reactive oxygen species suppress mir-328 targeting Cd44 in cancer cells and promote redox adaptation
Self-reported community sources consistently attribute this to the copper-induced vasodilatory effect rather than the GHK peptide itself
