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Regulation of energy metabolism in the growth plate and osteoarthritic chondrocytes

Figure 1 Figure 2 Once intracellular, choline is directed into various metabolic pathways, including 1) its oxidation to form mitochondrial betaine, 2) its acetylation to produce ACh, and 3) its initial phosphorylation followed by mobilization in the Kennedy pathway to generate cholie-containing phospholipids ( Figure 2 )

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Nuclear receptor liver X receptor is O -GlcNAc-modified in response to glucose