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Lancet Diabetes Endocrinol 7:344355 Mozaffarian D (2024) GLP-1 agonists for obesityA new recipe for success

Zepbound was FDA-approved in 2023 for long-term weight management in adults with obesity (with a body mass index of 30 or higher) and overweight (with a body mass index of 27 or higher) with at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol

Have low tolerance for gastrointestinal side effects - GLP-1 medications commonly cause nausea, vomiting, and other digestive symptoms that may take weeks or months to improve

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Choline: A nutrient that promotes liver health and fat processing

The various chemicals that induce liver enlargement associated with enzyme induction are presumed to be stimulating a hepatic physiological adaptation to an increased workload demand