The Rebound Question Here's what we do know: when people stop taking GLP-1 medications, weight regain is common
"Side effects are unavoidable." Nausea, constipation, fatigue, and reflux are common but often tied to how quickly medication is introduced and how you're eating
Eating behavior and appetite: Naltrexone/bupropion does not work like a GLP-1 active ingredient, but acts on central regulatory mechanisms in the brain
Older adults: standards of care in diabetes-2025
586 Nunes, M
Gradual dose escalation is crucial for mitigating AEs, while combination with other medications, including oral antidiabetic agents, and consideration of polypharmacy in older adults, as well as individualization of therapy, should consider comorbidities, gastrointestinal tolerability, and cost