Sometimes teens on GLP-1s can develop a rash or hives, which I have not seen in adults
In mouse and human organoids, treatment with SCFA led to an increase in the number of L-cells and glucose-induced GLP-1 secretion
However, fasted exercise is not appropriate for those taking insulin or sulphonylureas without specialist advice due to hypoglycaemia risk
Its an appealing prospectespecially since these drugs are offered at a fraction of the price of their name-brand counterparts and are often shipped overnight after a prospective patient fills out a quick online questionnaire
All references FDA: Concerns with unapproved GLP-1 drugs used for weight loss NEJM (2023): Retatrutide Phase 2 trial in obesity Eli Lilly: Phase 2 retatrutide results published in NEJM Eli Lilly (Dec 2025): Phase 3 TRIUMPH-4 topline results announcement ClinicalTrials.gov: NCT05882045 (TRIUMPH-3) Drugs.com: Retatrutide status & timeline Lilly Trials: TRIUMPH-3 summary page
By integrating GLP-1 medications into your weight loss program, Cape Fear Physical Medicine and Rehab provides effective tools to help you achieve and maintain a healthier weight and improve your overall well-being
