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Who May Experience Increased Injection Discomfort: Safety Considerations and Eligibility Certain patient populations report higher injection discomfort: those with lipodystrophy from prior insulin use, patients with increased skin sensitivity or pain disorders, and individuals with low subcutaneous fat (BMI below 18.5 in some cases)

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Common Risk Factors Poor nutritional intake Existing stress or burnout Hormonal fluctuations Major life transitions Unrealistic expectations about weight loss Some patients may notice anxiety symptoms become more noticeable during periods of poor sleep, inconsistent eating, or emotional stress while using Wegovy

Morning Injections: Ideal for those who prefer starting the day with their dose

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Understanding GLP-1s for diabetes, weight loss, and beyond, April 14, 2025 Harvard Health, Trying to lose weight