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Vitamin B12 also plays a role in the proper functioning of the nervous system and in the synthesis of DNA

Higher NAD is associated with SIRT1 activity, studied in relation to cellular repair, stress response, and aging pathways

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Steroid modulation of amino acid neurotransmitter receptors

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[59] demonstrated that pioglitazone enhanced cellular autophagy and mitigated the apoptotic effects induced by AGEs in tendon-derived stem cells